ZEXTRON

Description

Ondansetron Injection is an antiemetic used to prevent and treat nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It works by blocking serotonin receptors in the brain that trigger nausea.

Composition:

Each ml contains:

• Ondansetron Hydrochloride – 2 mg

Available strengths:

• 2 mg/ml (in 2 ml ampoule – total 4 mg dose)

Uses/Indications:

Ondansetron Injection is indicated for:

• Prevention of nausea and vomiting due to chemotherapy or radiotherapy
• Postoperative nausea and vomiting (PONV) prevention
• Nausea in gastrointestinal conditions

Dosage and Administration:

✅ Route of Administration:

• Intravenous (IV) or Intramuscular (IM) injection

✅ Dosage Guidelines:

• Chemotherapy-Induced Nausea and Vomiting (CINV):

• • Adults: 8 mg IV slowly before chemotherapy, followed by 8 mg after 8 hours

  • Children (≥6 months): 0.15 mg/kg IV before chemotherapy (max 8 mg)

• Postoperative Nausea and Vomiting (PONV):

  • Adults: 4 mg IV/IM before anesthesia induction

  • Children (≥1 month): 0.1 mg/kg IV (max 4 mg)

Precautions and Warnings:

• Contraindications:

• • Hypersensitivity to ondansetron or other 5-HT3 antagonists

• Special Precautions:

  • Use cautiously in patients with liver impairment

  • Monitor for QT prolongation in cardiac patients

  • Avoid use in pregnancy unless absolutely necessary

Side Effects:

Common side effects:

• Headache and dizziness
• Constipation or diarrhea
• Injection site reactions

Serious side effects (rare):

• Allergic reactions (rash, swelling, anaphylaxis)
• QT interval prolongation (irregular heartbeat)

Why Choose Our Ondansetron Injection?

✅ WHO-GMP Certified – Ensuring Quality & Safety
✅ Fast-Acting Relief for nausea and vomiting
✅ Available for PCD Pharma Franchise & Third-Party Manufacturing